91

Skip to main content

Department of Chemistry

  1. NSM Home
  2. Department of Chemistry
  3. People
  4. Faculty Profile

People

Faculty Profile

Naihao ChiangNaihao Chiang

Assistant Professor
Department of Chemistry

Office: Fleming, 139L
Contact: nchiang@central.uh.edu - 713-743-6621

Education: Ph.D., Northwestern University, 2017; B.S., University of Southern California, 2010

Postdoctoral Fellow, UCLA, 2017-2021

Our group focuses on developing and applying plasmonic-enhanced near-field optical techniques to investigate fundamental light-matter interactions at the quantum limit and their applications to emerging technologies. Specifically, we are interested in the chemical and biological processes at the solid-liquid interfaces with custom-built laser-coupled scanning probe microscopes for tip-enhanced Raman spectroscopy. Additionally, we are also interested in bridging the atomistic understanding to the mesoscopic world by exploring large-area uniform plasmonic metasurfaces.

Scanning Ion-Conductance Microscopy with Tip-Enhanced Raman Spectroscopy (SICM-TERS)

Ultraprecise Plasmonic Intracellular Delivery

Solid-liquid interfacial processes at the Angstrom scale

Plasmonic Metasurfaces

  • K99/R00 Pathway to Independence Award, NIH National Institute of Biomedical Imaging and Bioengineering, 2019
  • Division of Chemical Physics Young Investigator Travel Award, American Physical Society, 2018
  • Outstanding Researcher Award, International Institute for Nanotechnology, 2016
  • Dorothy M. and Earl S. Hoffman Travel Grant, American Vacuum Society, 2016
  • Award for an Outstanding Poster Presentation, Gordon Research Conference on Vibrational Spectroscopy, 2016
  • American Vacuum Society Nanometer-Scale Science and Technology Division Graduate Award, Finalist, 2015
  1. X. He, L. Scarabelli, and N. Chiang*, “Construction of a Scanning Ion-Conductance Microscope for Tip-Enhanced Raman Spectroscopy”, Anal. Chem. 2025, 97, 30, 16098.
  2. Y-C. Chen, C. Li, AM. Tareq, L.R. Madison*, and N. Chiang*, “Sub-Molecular Resolution Imaging of Self-Assembled Metallocene Dimers under Aqueous Environment”, Opt. Comm. 2025, 591, 132119.
  3. Y. Conti, X. He, Y-C. Chen, N. Chiang*, and L. Scarabelli*, “Enhanced Two-photon Excited Emission of Quantum Emitters by Colloidal Plasmonic Metasurfaces”, Adv. Photonics. Res. 2025, 6, 7, 2500075.
  4. X. He, AM. Tareq, K. Qi, Y.Conti, V. Tung, and N. Chiang*, “High-Resolution Distance Dependence Interrogation of Scanning Ion-Conductance Microscopic Tip-Enhanced Raman Spectroscopy Enabled by Two-Dimensional Molybdenum Disulfide Substrates”, Nano Lett. 2024, 24, 43, 13805.
  5. W. Naimi, G. Vinnacombe-Willson*, S. Saldana, L. Ronduen, H. Domjan, and N. Chiang*, “Teaching Acid-Base Fundamentals and Introducing pH using Butterfly Pea Flower Tea”, J. Chem. Educ. 2024, 101, 3, 1373.https://pubmed.ncbi.nlm.nih.gov/38516052/
  6. N. Chiang,* L. Scarabelli,* G. Vinnacombe-Willson,† L. Pérez, C. Dore, A. Mihi, P. S. Weiss and S. Jonas, “Large-scale Soft Lithographic Patterning of Plasmonic Nanoparticles” 2020, 3, 282.
  7. G. Vinnacombe-Willson,† N. Chiang, P. S. Weiss, S. Tolbert and L. Scarabelli, “Seeded-Growth Experiment Demonstrating Size- and Shape-Dependence on Gold Nanoparticle-Light Interactions”, J. Chem. Educ. 2020, 98, 546.
  8. G. Vinnacombe-Willson,† N. Chiang, L. Scarabelli, Y. Hu, L. Heidenreich, X. Li,† Y. Gong,† D. Inouye,† T. Fisher, P. S. Weiss and S. Jonas, “In Situ Shape Control of Thermoplasmonic Gold Nanostars on Oxide Substrates for Hyperthermia-Mediated Cell Detachment”, ACS Central Science 2020, 6, 11, 2105.
  9. J. Belling, L. Heidenreich, Z. Tian, A. Mendoza, T-T. Chiou, Y. Gong,† N. Chen, T. Young, N. Wattanatorn,† J. Park, L. Scarabelli, N. Chiang, J. Takahashi, S. Young, A. Stieg, S. De Oliveira, T. Huang, P. S. Weiss and S. Jonas, "Acoustofluidic Gene Delivery to Human Hematopoietic Stem and Progenitor Cells", Proc. Natl. Acad. Sci. 2020, 117, 10976.
  10. C. Zhao, X. Xu, A. Ferhan, N. Chiang, J. Jackman, Q. Yang, W. Liu, A. Andrews, N-J. Cho and P. S. Weiss, "Scalable Fabrication of Quasi-One-Dimensional Au Nanoribbons for Plasmonic Sensing" Nano Lett. 2020, 20, 1747.
  11. S. Wang,† N. Chiang, H. Gao, N. Wattanatorn,† K. Barr,† P. Sautet, A. Alexandrova and P. S. Weiss, "Distribution of Photoinduced Charges in Titanyl Phthalocyanine Self-Assembled Monolayer", Chem. Mater. 2019, 31, 10109.
  12. S. Wang,† N. Wattanatorn,† N. Chiang, Y. Zhao, M. Kim, H. Ma, A. Jen and P. S. Weiss, "Photo-Induced Charge Transfer in Single-Molecule p-n Junctions", J. Phys. Chem. Lett. 2019, 10, 2175.
  13. D. Nguyen, G. Kang,† N. Chiang, X. Chen, T. Seideman, M. Hersam, G. Schatz and R. P. Van Duyne, "Probing Molecular-Scale Catalytic Interactions between Oxygen and Cobalt Phthalocyanine Using Tip-Enhanced Raman Spectroscopy", J. Am. Chem. Soc. 2018, 140, 5948.
  14. N. Chiang, N. Jiang, L. Madison, E. Pozzi, G. Goubert, M. Wasielewski, T. Seideman, M. Ratner, M. Hersam, G. Schatz and R. P. Van Duyne, "Probing Intermolecular Vibrational Symmetry Breaking in Self-Assembled Monolayers with Ultrahigh Vacuum Tip-Enhanced Raman Spectroscopy", Am. Chem. Soc. 2017, 139, 18664.
  15. X. Xu, Q. Yang, N. Wattanatorn,† C. Zhao, N. Chiang, S. J. Jonas and P. S. Weiss, "Multiple-Patterning Nanosphere Lithography for Fabricating Periodic Three-Dimensional Hierarchical Nanostructures", ACS Nano 2017, 11, 10384. [Cover Article]
  16. D. Kurouski, N. Large, N. Chiang, A-I. Henry, T. Seideman, G. C. Schatz and R. P. Van Duyne, "Unraveling Near- and Far-Field Relationship of 2D SERS Substrates Using Wavelength-Scan Surface-Enhanced Raman Excitation Spectroscopy (WS-SERES)", J. Phys. Chem. C 2017, 121, 14737.
  17. A. Zrimsek, N. Chiang, M. Mattei,† S. Zaleski, C. Chapman, M. McAnally, A-I. Henry, G. Schatz and R. P. Van Duyne, "Probing Single Molecule Chemistry with SERS and TERS", Chem. Rev. 2017, 117, 7583.
  18. E. Pozzi, G. Goubert, N. Chiang, N. Jiang, C. Chapman, M. McAnally, A-I. Henry, T. Seideman, G. Schatz, M. Hersam and R. P. Van Duyne, "Ultrahigh Vacuum Tip-Enhanced Raman Spectroscopy", Chem. Rev. 2017, 117, 4961. [Cover Article]
  19. N. Chiang, X. Chen, G. Goubert, D. Chulhai, X. Chen, E. Pozzi, N. Jiang, M. Hersam, T. Seideman, L. Jensen and R. P. Van Duyne, "Conformational Contrast of Surface-Mediated Conformational Switches Yields Angstrom-Scale Spatial Resolution in Ultrahigh Vacuum Tip-Enhanced Raman Spectroscopy", Nano Lett. 2016, 16, 7774. [C&EN News Article]
  20. B. Sharma, L. Madison, P. Bugga, A-I. Henry, M. Blaber, N. Greeneltch, N. Chiang, M. Mrksich, G. Schatz and R. P. Van Duyne, "Bisboronic Acids for Selective, Physiologically Relevant Direct Glucose Sensing with Surface-Enhanced Raman Spectroscopy", J. Am. Chem. Soc. 2016, 38, 18952.
  21. E. Pozzi, N. Gruenke, N. Chiang, D. Zhdanov, N. Jiang, T. Seideman, G. Schatz, M. Hersam and R. P. Van Duyne, "Operational Regimes in Pulsed-Excitation Ultrahigh-Vacuum SERS", J. Phys. Chem. Lett. 2016, 7, 2971.
  22. N. Jiang, D. Kurouski, E. Pozzi, N. Chiang, M. Hersam and R. P. Van Duyne, "Tip-Enhanced Raman Spectroscopy: From Concepts to Practical Applications", Chem. Phys. Lett. 2016, 659, 16. [Cover Article]
  23. N. Jiang, N. Chiang, L. Madison, E. Pozzi, M. Wasielewski, T. Seideman, M. Ratner, M. Hersam, G. Schatz and R. P. Van Duyne, "Nanoscale Chemical Imaging of a Dynamic Molecular Phase Boundary with Ultrahigh Vacuum Tip-Enhanced Raman Spectroscopy", Nano Lett. 2016, 16, 3898.
  24. D. Kurouski, N. Large, N. Chiang, N. Greeneltch, K. T. Carron, T. Seideman, G. C. Schatz and R. P. Van Duyne, "Unraveling Near-Field and Far-Field Relationships of 3D SERS Substrates - A Combined Experimental and Theoretical Analysis", Analyst 2016, 141, 1779.
  25. N. Chiang, N. Jiang, D. Chulhai, E. Pozzi, M. Hersam, L. Jensen, T. Seideman and R. P. Van Duyne, "Molecular-Resolution Interrogation of a Porphyrin Monolayer by Tip-Enhanced Raman and Fluorescence Spectroscopy", Nano Lett. 2015, 15, 4114.
  26. P. P. Pal, N. Jiang, M. D. Sonntag, N. Chiang, E. T. Foley, M. C. Hersam, R. P. Van Duyne and T. Seideman, "Plasmon Enhanced Transport in Tip-Enhanced Raman Spectroscopic Junctions", J. Phys. Chem. Lett. 2015, 6, 4210.
  27. E. A. Pozzi, M. D. Sonntag, N. Jiang, N. Chiang, T. Seideman, M. C. Hersam, and R. P. Van Duyne, "Ultrahigh Vacuum Tip-Enhanced Raman Spectroscopy with Picosecond Excitation", J. Phys. Chem. Lett. 2014, 5, 2657.
  28. E. Loginov, L. F. Gomez, N. Chiang, A. Halder, N. Guggemos, V. V. Kresin and A. F. Vilesov, "Photoabsorption of AgN(N∼6–6000) Nanoclusters Formed in Helium Droplets: Transition from Compact to Multicenter Aggregation", Phys. Rev. Lett. 2011, 106, 233401.